Damascus hotels like this one are convenient to shops, Turkish baths, coffee shops, and museums in the city. Guests of the Semiramis Hotel Damascus may wish to enjoy the shopping district of Souq al-Hamidiyya and pick up some silk or copper goods, or go on a day trip to see the October War Panorama. At night, there are a variety of restaurants to enjoy, and guests can enjoy the view at night of the city lights from Mount Qasioun. The closest major airport to the Semiramis Hotel Damascus is the Damascus International Airport.

The Semiramis Hotel Damascus offers 114 rooms and a non-smoking floor is available. Amenities in the rooms include air conditioning, heat, phones, safes, televisions with satellite channels, showers, hair dryers, mini bars, and work desks.

The conference rooms at this hotel can hold up to 800 people, and the business center is helpful for guests with business and Internet needs. The Semiramis Hotel Damascus offers restaurants and bars on the premises, plus there is a fitness facility and sauna for guests. The swimming pool is perfect for fun and relaxation, and there is a beauty salon onsite.